iOmx Therapeutics AG
ABOUT US iOmx Therapeutics is a clinical-stage company in the field of immuno-oncology located in Martinsried/Munich, Germany. We are focusing on the development of first-in-class cancer immunotherapies, addressing novel immune evasion biologies, which are hijacked by tumors and their microenvironment. We are looking for highly motivated, self-driven and competent colleagues who share our vision and wish to contribute to translating this vision into reality. (Senior) Research Associate – Tumor (Immune) Biology (gn) Festanstellung, Vollzeit iOmx Therapeutics AG As a part of the Research Department, you will contribute to the mechanistic understanding of novel immune-checkpoint targets and actively participate in the screening and selection of functional drug candidates against them for further development. You will work in a modern, semi-automated laboratory and will be eager to continuously evaluate and implement new state-of-the-art techniques to advance our target-tailored drug discovery and characterization efforts. Some of your daily tasks will include: Culture and maintenance of primary immune cells and immortalized cell lines Immune cell separation from Leukopacks and buffy coats and purity assessment In vitro primary immune cell-based experiments with execution of immunological endpoint assays such as flow cytometry, immune cytotoxicity assays, ELISA, multiplex, and live cell imaging Perform molecular biology and protein analytic assays such as qPCR, Western Blotting, CRISPR/Cas-based gene editing, transfection and transduction of cells Participate in routine laboratory management and organizational tasks Execution of experiments both independently and in a team, including diligent analysis, documentation, and presentation of your results in internal team meetings You hold a university degree (Bachelor’s or Master’s) in biology, molecular medicine, biotechnology, or a related field, or have completed a vocational training as laboratory assistant such as BTA, MTA, CTA and have at least 3 years of relevant work experience, preferably in an industry setting You possess extensive hands-on experience in the execution of immunological endpoint assays such as flow cytometry and ELISA Ideally you have experience in genome editing and/or in transfection/transduction of primary human immune cells or cell lines You have experience in operating semi-automatic liquid handling devices to conduct large scale experiments, ensuring comprehensive and accurate testing of a wide range of biological parameters You are experienced in using data analysis software such as GraphPad Prism and Flow Jo You are motivated to work independently and collaboratively in a fast-paced environment to meet project goals You are fluent in English (spoken and written) We are a young biotechnology company with about 50 employees in Martinsried/Munich. We are working in flat hierarchies with short decision-making processes and offer a rewarding career in a welcoming, trusting, and international work environment. By joining us you can expect the following: Opportunity for personal development Growth-oriented and innovation-driven company culture 30 days paid vacation Flexible working time and much more
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