The Niederholtmeyer Lab for Synthetic Biology at TUM Campus Straubing for Biotechnology and Sustainability invites applications for a PhD position in cell-free synthetic biology. We offer a project on feedback control of dynamic condensate assembly and disassembly.<\/b><\/p>\n
The Niederholtmeyer Lab is a synthetic biology research group at the TUM Campus Straubing for Biotechnology and Sustainability. Our work centers on cell-free systems and the engineering of life-like compartments.<\/p>\n
THE PROJECT
\nBiomolecular condensates are fascinating cellular structures that can rapidly assemble and disassemble \u2013 a property we want to harness to build self-regulating synthetic compartments. We are offering a PhD position focused on engineering feedback mechanisms that control condensate assembly and disassembly. The project combines cell-free expression, microfluidics, and fluorescence microscopy to build and characterize condensate systems that switch engineered functions on and off in response to their own assembly state. You will characterize the dynamics of condensate formation and design gene expression or enzyme activity switches triggered by condensate assembly. Based on this you will work toward achieving periodic, self-regulated condensate cycles.<\/p>\n
YOUR PROFILE
\n\u2022 MSc degree in biochemistry, biophysics, molecular biology, synthetic biology, or a closely related field
\n\u2022 Enthusiasm for interdisciplinary, collaborative research at the interface of biophysics, molecular biology, and synthetic biology
\n\u2022 Prior experience with cell-free expression systems, microfluidics, molecular cloning, microscopy and quantitative analyses is a plus.
\n\u2022 Strong written and verbal communication skills in English<\/p>\n
THE ENVIRONMENT AND THE POSITION
\n\u2022 Location: TUM Campus Straubing for Biotechnology and Sustainability
\n\u2022 Position: TV-L E13 (65%), with the opportunity to pursue a doctoral degree (PhD)
\n\u2022 Start date: from July 2026
\n\u2022 Research community: The position is embedded in the BioSysteM Cluster of Excellence, offering access to cutting-edge infrastructure, interdisciplinary collaborations, and an active PhD network spanning multiple institutions in the Munich area
\n\u2022 More information: https:\/\/syb.cs.tum.de , https:\/\/hn-lab.org , https:\/\/www.biosystem.design<\/p>\n
APPLICATION
\nPlease submit your application as a single PDF including:
\n\u2022 Motivation letter
\n\u2022 CV
\n\u2022 Academic transcripts
\n\u2022 Contact details for at least two references<\/p>\n
Applications should be submitted until April 26, 2026 to: jobs_syb@cs.tum.de<\/p>\n
Contact: Prof. Henrike Niederholtmeyer, Professorship for Synthetic Biology<\/p>\n
TUM is an equal opportunity employer. Qualified women are therefore particularly encouraged to apply.<\/p>\n
Die Stelle ist f\u00fcr die Besetzung mit schwerbehinderten Menschen geeignet. Schwerbehinderte Bewerberinnen und Bewerber werden bei ansonsten im wesentlichen gleicher Eignung, Bef\u00e4higung und fachlicher Leistung bevorzugt eingestellt.<\/p>\n<\/div>\n<\/div>\n
Hinweis zum Datenschutz:<\/b> Kontakt:\u00a0jobs_syb@cs.tum.de<\/a><\/span><\/p>","protected":false},"author":6,"featured_media":0,"template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_promoted":"","_job_location":"Straubing","_application":"jobs_syb@cs.tum.de","_company_name":"","_company_website":"","_company_tagline":"","_company_twitter":"","_company_video":"","_filled":0,"_featured":0,"_remote_position":0,"_job_salary":"","_job_salary_currency":"","_job_salary_unit":""},"job-categories":[],"job-types":[],"class_list":["post-246277","job_listing","type-job_listing","status-expired","hentry"],"wpcf_dashboard":"
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